![]() Electrotherapy device for cell therapy or cell stimulation.
专利摘要:
A therapy device for cell stimulation or cell therapy comprises a housing (12) which has an electrode (1), a generator (3) for generating high-frequency pulses, a processor unit (6) comprising a control, regulation and calculation module, a memory unit (9 ), an operating element (5), a controllable modulator (4), by means of which the generator (3) can be controlled. An energy store (10) arranged in the housing (12) is provided to supply energy for operating the therapy device, so that the therapy device can be operated wirelessly. 公开号:CH715327A2 申请号:CH01144/19 申请日:2019-09-11 公开日:2020-03-13 发明作者:Erdmann Raimund;Laubscher Urs 申请人:Activcell Ag; IPC主号:
专利说明:
The present invention relates to a therapy device for cell therapy or cell stimulation according to the preamble of claim 1. Therapy devices are known from the prior art, which use the technology of physiological electrostimulation, also referred to in the literature as electrotherapy. Such therapy devices are based on the principle of delivering electrical energy to the biological cell. This technology is used in medicine for so-called high-frequency therapy. An electrical field generated with an HF generator is combined with a delivery device for the pulsed delivery of the HF power to the cell in order to enable cell stimulation. The field of application of the therapy device according to the invention is in the field of wellness applications, fitness, cosmetics, pain reduction, wound healing, for cell therapy or further cell stimulation for treatment in humans or animals. [0004] Document DE 2 822 892 A1 shows an example of such a therapy device, namely a device for maintaining the negative potential of human, animal and plant cells and / or for penetrating substances into the cells. A generator which can be influenced by means of a control circuit generates high-frequency pulses of adjustable repetition frequency and duration, and a circuit generates a direct voltage and a pulsating equilibrium voltage for ionization and pulses of a certain shape and variable repetition frequency for faradization of the tissue to be treated. A therapy session is carried out over a predetermined time interval. Although good results are achieved with this known therapy device with regard to its intended use, the following disadvantages occur for the user during operation:The device is cumbersome to use during therapy, since only a wired power supply is available,the energy level is set via a manual control on the power supply unit,the pulse frequency of the energy output can only be varied in a small range, namely in a range from 10 to 1000 Hz,the emitted energy cannot be influenced in its signal form. Thus, a sustainable therapy success is restricted, an application of case-specific pulse forms is not possible, so that an excessive number of recurrent therapy sessions must be held and / or there is a limited effect on the cells. Based on this prior art, the invention has for its object to provide a therapy device which overcomes the disadvantages of the prior art. In particular, it is an object of the invention to develop a therapy device that is easier to use, the pulse frequency and / or energy delivery and / or the signal shape can be individually matched to the intended treatment or therapy by the pulse frequency and / or the energy delivery and / or the signal shape can be varied over a wide range. The object is solved by the features of claim 1. Advantageous embodiments of the therapy device are the subject of claims 2 to 9. The use of the therapy device for cell stimulation is the subject of claim 10. The therapy device has an improved signal output, which is configured or preprogrammed by the user depending on the type of therapy. The therapy device has significantly improved manageability due to the integrated energy storage unit, which enables wireless operation. [0010] According to the invention, this is made possible by at least one of the following features:A variable signal curve, for example a variable frequency of the high-frequency field, which is emitted via an electrode,the regulation of the intensity of the emitted energy, the emitted power typically remaining constant and independent of the position and / or the type of the electrodes,the increase in manageability through an energy storage unit arranged in the housing, which has its own internal power supply and is operated by means of energy cells, typically by means of a rechargeable battery. The wireless application can be facilitated and improved by means of a new, previously unused physical principle in the therapy application. According to one embodiment, a capacitive coupling is used so that the energy flow of the high-frequency field from the user to the treatment object can take place. According to this exemplary embodiment, the electrode is capacitively coupled to the user and connects the user to the treatment object by means of the electrode. The body of the user and the treatment object ensure potential equalization via the capacitive coupling. The advantage of the invention in relation to the controllable, programmable and its signal form adjustable energy delivery is that different forms of therapy experience an optimization. [0013] According to an exemplary form of therapy, the energy is emitted across the surface via the variable pulse frequency of the energy output with simultaneous modulation of the signal form. This influences, among other things, the term “skin effect” known to the person skilled in the art. With this effect, the electrons, which reach the treatment object via the high-frequency voltage emitted via the electrode, are more strongly forced onto the surface of the treatment object. With a lower amplitude and / or frequency modulation (AM / FM) there is a reduction in the skin effect, with the result that the depth of penetration and the duration of the energy release takes place in a more targeted manner. The modulation is carried out by the user by actuating control elements of the therapy device and / or by a therapy device designed according to the form of therapy, which reads out the required modulation from a memory unit. In a further embodiment, the energy output is measured by means of a sensor, for example by measuring a voltage and / or a current, and the measurement result is fed to the processor unit. The processor unit contains a control module, by means of which different states can be controlled depending on the therapy method. According to one embodiment, the energy output is modulated during the modulation in such a way that the energy output follows its own selectable signal form or one that can be called up from the storage unit. According to one embodiment, the energy output is stabilized by the wireless use during therapy or the modulated signal form, regardless of the electrode used, the different coupling factor of the capacitive coupling. In a further embodiment, the measured values determined by the sensor can be made available as a signal to the processor unit, which can process the measured values as measured data. In particular, the units or measurement variables mentioned below can be calculated using the calculation module. The units can optionally be displayed via a display element, output via an interface for information exchange or stored in a storage unit. The units can comprise at least one element from the following list:total energy released in a certain time interval,Signal form and type of modulation (AM / FM) during therapy,Removal of the electrode and time interval of one or more interruptions,Regulation of internal energy management,Detection of faulty electrodes. Further calculations are conceivable which document and register the course of therapy for each treatment object. Furthermore, further calculations including external data that are read in via the interface are conceivable, which increase and prove the success of the therapy. For this purpose, the processor unit can carry out any type of calculations, typically these are regulatory and / or statistical calculations. [0021] The results of the calculations can in turn be fed into the control module of the processor unit and influence the signal curve, the modulation. A therapy effect can be used to generate a learning effect for a later therapy session from an earlier therapy session. These therapy data can be communicated to other therapy devices via the interface for information exchange and thus ensure that a continuous improvement in quality is made possible by each use of the therapy device according to the invention. The capacitive coupling can be done by coupling the user and the treatment object with a conductor surface on the housing of the therapy device. Here it is conceivable that the housing itself is designed to be electrically conductive, that is to say has at least one electrically conductive or conductive surface, or the housing has an internal conductive or conductive surface. The conductive or conductive surface itself can be designed as a wire, as a surface or as a three-dimensional object. The energy supply to the energy storage unit can take place via a charging system. In one embodiment, this charging system comprises a contact plug and can obtain the energy required from a commercially available charging station. In another possible embodiment, the energy storage unit is charged via an induction loop which is attached in the housing. This induction loop forms a secondary coil of a transmission transformer. An energy flow can thus take place by means of the primary coil installed in the charging station when the therapy device is in the effective field of the charging station. Such charging systems are meanwhile available in a standardized manner in the electrical industry. The invention is explained in more detail using an exemplary embodiment which is illustrated in the drawings. It shows:<tb> Fig. 1: <SEP> a diagram of an exemplary embodiment for a therapy device. 1 schematically shows a therapy device for cell therapy, comprising an electrode 1, a generator 3 for generating high-frequency pulses, a processor unit 6 comprising a control, regulation and calculation module, a memory element 9 and control elements 5. [0026] The therapy device can comprise at least one interface 8 for the exchange of information. The therapy device further comprises a memory unit 9 and a controllable modulator 4, which controls the generator 3. The energy supply for operating the therapy device takes place by means of an internal energy storage unit 10. The housing 12 can contain at least one display element 7, by means of which in particular therapy and operating data can be displayed. In addition, the therapy device comprises a sensor 2, which measures the voltage and / or the current delivered via the electrode 1, wherein the energy delivered via the electrode 1 can be determined from the measured voltage or the measured current. The current and / or the voltage delivered via the electrode 1 are thus detected as measured values by means of the sensor. The measured values are digitized and stored in the memory unit 9 as measured data. The energy output can be determined from the measurement data by means of the calculation module of the processor unit 6. From the measurement data for current and / or voltage stored in the memory unit 9 with a time stamp, the course of the energy emitted by the electrode 1 can be determined by means of the calculation module of the processor unit 6. The determined voltages and / or currents can alternatively also be recorded by a recording device and converted into measurement data, so that the time profile of the energy output by the electrode 1 can be determined from the recorded measurement data for the voltage and the current. [0030] All components of the therapy device can be arranged in a housing 12. In particular, the housing 12 and / or the generator 3 can be designed such that the housing or the generator form a pole of a capacitor, which enables capacitive coupling. According to one embodiment, the therapy and operating data from the memory unit 9 are designed to be readable and writable. The data stored in the storage unit 9 can serve to influence the course of therapy. According to one exemplary embodiment, the therapy and operating data can be calculated and processed in the processor unit 6 for control instructions, taking into account the measured values measured by the sensor 2, which can be stored as data in the storage unit. The control instructions can be used to control the modulator 4. The control of the modulator 4 can in particular take place in such a way that the energy output is constant and is independent of the signal form. In particular, the control of the modulator 4 can take place in such a way that any signal form is generated in the generator 3, typically a combination of amplitude and frequency modulation can take place. According to an embodiment, the housing 12 contains an electrically conductive or conductive surface, for example a conductive plastic or a plastic coated with an electrically conductive material. According to one embodiment, the energy storage unit 10 can be designed as a rechargeable element, typically as a lithium-ion element or as a supercapacitor. The energy delivered via the electrode 1 can be used for cell stimulation or cell therapy. Reference list [0039]<tb> 1 <SEP> electrode (s)<tb> 2 <SEP> sensor for measuring the waveform, energy<tb> 3 <SEP> generator especially high voltage and high frequency generator<tb> 4 <SEP> modulator<tb> 5 <SEP> control element<tb> 6 <SEP> processor unit comprising a control rule and<tb> <SEP> calculation module<tb> 7 <SEP> display element<tb> 8 <SEP> Interface for information exchange<tb> 9 <SEP> storage unit<tb> 10 <SEP> energy storage unit<tb> 11 <SEP> charging system for energy consumption<tb> 12 <SEP> housing
权利要求:
Claims (10) [1] 1. Therapy device for cell stimulation or cell therapy, comprising a housing (12) which has an electrode (1), a generator (3) for generating high-frequency pulses, a processor unit (6) comprising a control, regulation and calculation module, a memory unit (9), contains at least one control element (5) and a controllable modulator (4), by means of which the generator (3) can be controlled, characterized in that an energy storage unit (10) arranged in the housing (12) for energy supply for operating the therapy device is provided so that the therapy device can be operated wirelessly. [2] 2. Therapy device according to claim 1, wherein the housing (12) contains a display element (7), by means of which in particular therapy and operating data can be displayed. [3] 3. Therapy device according to one of the preceding claims, wherein the electrode (1) comprises a sensor (2), by means of which the current or the voltage delivered via the electrode (1) can be detected as measured values, the measured values being digitizable in measured data, wherein the measurement data can be stored in the memory unit (9), the energy output and / or the time profile of the energy output by the electrode (1) being ascertainable by means of the calculation module of the processor unit (6). [4] 4. Therapy device according to claim 3, wherein by means of the control module of the processor unit (6) the modulator (4) is regulated on the basis of the measurement data, in particular for regulating a constant energy output and / or for regulating which is independent of the signal form, so that any signal form can be generated in the generator (3), for example a combination of amplitude and frequency modulation. [5] 5. Therapy device according to one of claims 3 or 4, wherein the measurement data can be used by means of the control module of the processor unit (6) to control a course of therapy. [6] 6. Therapy device according to claim 5, wherein the measurement data in the processor unit (6) can be linked with a time stamp, wherein the measurement data linked with the time stamp can be stored in the storage unit for storing the course of therapy. [7] 7. Therapy device according to one of the preceding claims, wherein the housing (12) or the generator (3) are designed as one of the poles of a capacitor for capacitive coupling. [8] 8. Therapy device according to one of the preceding claims, wherein the energy storage unit (10) is designed as a rechargeable element, typically as a lithium-ion element or as a supercapacitor. [9] 9. Therapy device according to one of the preceding claims, wherein the housing (12) contains electrically conductive or conductive surface, for example a conductive plastic or a plastic coated with an electrically conductive material. [10] 10. Use of the therapy device according to one of the preceding claims for cell stimulation or cell therapy.
类似技术:
公开号 | 公开日 | 专利标题 DE102010004307B4|2013-01-31|Magnetic stimulation with freely selectable pulse shape DE69928383T2|2006-08-03|DEVICE FOR CONTROLLING THE GENERATION OF ELECTRICAL FIELDS EP1827586B1|2013-02-20|Device for desynchronizing neuronal brain activity DE2748780C2|1986-01-30|Device for treating living tissues and / or cells by means of pulses of opposite polarity DE102013211859B4|2015-07-16|Magnetic stimulator for stimulating a tissue through a magnetic field EP0784992A2|1997-07-23|Treatment device for malignant changes of tissue WO2008138305A1|2008-11-20|Stimulation device EP2965780B1|2017-02-01|Device for controlling the electric charge on stimulating electrodes EP0087617A1|1983-09-07|Medical apparatus for physical therapy, especially electro-medical stimulation apparatus DE2116869A1|1971-10-28|Electrical device for promoting the formation of new bone and tissue substance DE102005031427B4|2008-05-29|A programmable device and method for optimizing and real-time monitoring of gene transfection based on a user-configured arbitrary waveform pulse train DE102016122691A1|2018-05-24|Device for influencing biological processes in a living tissue CH715327A2|2020-03-13|Electrotherapy device for cell therapy or cell stimulation. EP3183032B1|2019-02-20|Device for effective invasive neurostimulation by means of varying stimulus sequences DE1812314A1|1970-06-25|Pulse current therapy device to influence the skin resistance EP0774273A2|1997-05-21|Method and device for diagnosis, for improving performance and for restoration of pertubed nerve and muscle activities EP0165285B1|1988-09-07|Electrical circuit for medical apparatus for producing a varying magnetic field DE102017122938A1|2019-04-04|Device for automatic selection of light color with combined micro current and light therapy DE1648905A1|1971-05-27|Process for the thermal investigation and influencing of the condition of media, in particular of biological tissue, as well as a device for carrying out this process DE19801351B4|2005-04-14|Low frequency therapy device DE809701C|1951-08-02|Device for stimulating physiological functions in living beings, in particular in humans EP0569616A1|1993-11-18|Device for applying electrical pulse to living tissues DE102017108084A1|2018-10-18|Pulse source and method for magnetic inductive nerve stimulation DE2462934C2|1983-09-01|Pulse device for acupuncture treatment DE102012203192B4|2015-07-02|CONCEPT FOR STIMULATING NERVOUS CELLS
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2021-01-29| PFA| Name/firm changed|Owner name: ACTIVCELL GROUP AG, CH Free format text: FORMER OWNER: ACTIVCELL AG, CH |
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申请号 | 申请日 | 专利标题 CH10722018|2018-09-11| 相关专利
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